LMPD Database

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LMP012408

Record overview

LMPD IDLMP012408
Gene ID24450
SpeciesMacaca mulata (Rhesus monkey)
Gene Name3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
Gene SymbolHmgcs2
SynonymsHmgcs1; Mt3h3mg;
Alternate nameshydroxymethylglutaryl-CoA synthase, mitochondrial; HMG-CoA synthase; hydroxymethylglutaryl-CoA synthase 2; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutary-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial);
Chromosome2
Map Location2q34
SummaryHMG-CoA cycle enzyme that catalyzes a step in ketone-body biosynthesis [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Hmgcs2

Proteins

hydroxymethylglutaryl-CoA synthase, mitochondrial precursor
Refseq ID:NP_775117
Protein GI:401461794
UniProt ID:Q68G44
mRNA ID:NM_173094
Length:508
RefSeq Status:
MQRLLAPARRVLQVKRVMQESSLSPAHLLPAAQQRFSTIPPAPLAKTDTWPKDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQE
DINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVY
PSGNARPTGGAGAVAMLIGPKAPLVLEQGLRGTHMENAYDFYKPNLASEYPLVDGKLSIQCYLRALDRCYAAYRRKIQNQWKQAGNNQPFTLDDVQYMIF
HTPFCKMVQKSLARLMFNDFLSSSSDKQNNLYKGLEAFKGLKLEETYTNKDVDKALLKASLDMFNKKTKASLYLSTNNGNMYTSSLYGCLASLLSHHSAQ
ELAGSRIGAFSYGSGLAASFFSFRVSKDASPGSPLEKLVSSVSDLPKRLDSRRRMSPEEFTEIMNQREQFYHKVNFSPPGDTSNLFPGTWYLERVDEMHR
RKYARRPV
 

transit_peptide: 1..37
inference: non-experimental evidence, no additional details recorded
note: Mitochondrion (Probable); propagated from UniProtKB/Swiss-Prot (P22791.1)
calculated_mol_wt: 4215
peptide sequence: 
MQRLLAPARRVLQVKRVMQESSLSPAHLLPAAQQRFS

mat_peptide: 38..508
product: Hydroxymethylglutaryl-CoA synthase, mitochondrial
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P22791.1)
calculated_mol_wt: 52689
peptide sequence: 
TIPPAPLAKTDTWPKDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDK
SKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLVLEQGLRGTHMEN
AYDFYKPNLASEYPLVDGKLSIQCYLRALDRCYAAYRRKIQNQWKQAGNNQPFTLDDVQYMIFHTPFCKMVQKSLARLMFNDFLSSSSDKQNNLYKGLEA
FKGLKLEETYTNKDVDKALLKASLDMFNKKTKASLYLSTNNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSKDASPGSPLEK
LVSSVSDLPKRLDSRRRMSPEEFTEIMNQREQFYHKVNFSPPGDTSNLFPGTWYLERVDEMHRRKYARRPV