LMPD Database

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LMP012398

Record overview

LMPD IDLMP012398
Gene ID24298
SpeciesMacaca mulata (Rhesus monkey)
Gene Namecytochrome P450, family 21, subfamily a, polypeptide 1
Gene SymbolCyp21a1
Synonyms21-OH; Cyp21;
Alternate namessteroid 21-hydroxylase; 21-OHase; P-450c21; P450-C21; cytochrome P-450c21; cytochrome P450 XXI; cytochrome P450-C21; cytochrome P450 21 steroid 21 hydroxylase; cytochrome P450, subfamily 21A, polypeptide 1; Cytochrome P450 subfamily XXI (steroid 21-hydroxylase); cytochrome P450, subfamily XXI (steroid 21-hydroxylase);
Chromosome20
Map Location20p12
Summaryconverts progesterone to deoxycorticosterone via 21-hydroxylation in the adrenal gland and possibly in peripheral astrocytes and CNS [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Cyp21a1

Proteins

steroid 21-hydroxylase
Refseq ID:NP_476442
Protein GI:259906405
UniProt ID:F1LRG0
mRNA ID:NM_057101
Length:493
RefSeq Status:
MLLPGLLLLLLLLLLAGTRWLWGQWKLWKLRLPPLAPGFLHFLQPNLPVYLFGLAQKLGPIYRIRLGLQDVVVLNSNKTIEEALIQKWVDFAGRPQILDG
KMNFDLSMGDYSLTWKAHKKLSRSALVLGMRDSMEPLVEQLTQEFCERMRAQAGASVAIHKEFSLLTCSIISCLTFGDKQDSTLLNATHSCVRDLLKAWN
HWSVQILDIIPFLRFFPNPGLWKLKQFQESRDHIVMQELKRHKDSLVAGQWKDMIDYMLQGVEKQRDARDPGQLHERHVHMSVVDLFVGGTETTAATLSW
AVAFLLHHPEIQKRLQEELDLKLAPSSQLLYKNRMQLPLLMATIAEVLRLRPVVPMALPHRATKASSISGYDIPKDTIIIPNIQGANLDEMVWELPSKFW
PDRFLESGKSPRIPTFGCGARVCLGEPLARLELFVVLARLLQTFTLLPPPDGTLPSLQPLPYTGINLLIPPFQVRLQPRNLAPQDQGQKSSTG