LMPD Database

LMP012119

UniProt Annotations

Entry Information
Gene Namedefender against cell death 1
Protein EntryA7E2L0_DANRE
UniProt IDA7E2L0
SpeciesZebrafish
Comments
Comment typeDescription
Catalytic ActivityDolichyl diphosphooligosaccharide + [protein]- L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
FunctionEssential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the DAD/OST2 family.
Subcellular LocationEndoplasmic reticulum membrane ; Multi-pass membrane protein .
SubunitComponent of the oligosaccharyltransferase (OST) complex.