LMPD Database

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LMP011959

UniProt Annotations

Entry Information
Gene NameCTD nuclear envelope phosphatase 1 regulatory subunit 1
Protein EntryNEPR1_DANRE
UniProt IDQ561X0
SpeciesZebrafish
Comments
Comment typeDescription
FunctionMay form with the serine/threonine protein phosphatase ctdnep1 an active complex dephosphorylating and activating lipins. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity). {ECO:0000250}.
SimilarityBelongs to the CNEP1R1 family. {ECO:0000305}.
Subcellular LocationNucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}.