LMPD Database

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LMP011511

UniProt Annotations

Entry Information
Gene Namefatty acid desaturase 2
Protein EntryFADS2_DANRE
UniProt IDQ9DEX7
SpeciesZebrafish
Comments
Comment typeDescription
DomainThe histidine box domains may contain the active site and/or be involved in metal ion binding.
FunctionFatty acid desaturase with both Delta(5) and Delta(6) activities. Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) (By similarity). {ECO:0000250}.
PathwayLipid metabolism; polyunsaturated fatty acid biosynthesis.
SimilarityBelongs to the fatty acid desaturase family. {ECO:0000305}.
SimilarityContains 1 cytochrome b5 heme-binding domain. {ECO:0000255|PROSITE-ProRule:PRU00279}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.