LMPD Database

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LMP010922

UniProt Annotations

Entry Information
Gene Nameplastidial pyruvate kinase 2
Protein EntryPKP2_ARATH
UniProt IDQ9FLW9
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiespH dependence: Optimum pH is 7.8-8.0. {ECO:0000269|PubMed:17557808, ECO:0000269|PubMed:17892448};
Catalytic ActivityATP + pyruvate = ADP + phosphoenolpyruvate.
CofactorName=K(+); Xref=ChEBI:CHEBI:29103; Evidence={ECO:0000269|PubMed:17557808};
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:17557808};
Developmental StageIn seeds, accumulates in endosperm and embryo. In torpedo-shaped embryos, restricted to the hypocotyl and in the outer parts of the young cotyledons. In later embryo stages, present in all tissues except root tips. {ECO:0000269|PubMed:17892448}.
Disruption PhenotypeReduced plastidial pyruvate kinase activity and altered seed oil content leading to wrinkled seeds, retarded embryo elongation and reduced seed germination. {ECO:0000269|PubMed:17557808, ECO:0000269|PubMed:17892448}.
FunctionRequired for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination. {ECO:0000269|PubMed:17557808, ECO:0000269|PubMed:17892448, ECO:0000269|PubMed:17965177}.
InductionRepressed by cadmium. {ECO:0000269|PubMed:16502469}.
PathwayCarbohydrate degradation; glycolysis; pyruvate from D- glyceraldehyde 3-phosphate: step 5/5.
SimilarityBelongs to the pyruvate kinase family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast stroma. Mitochondrion.
SubunitOligomer of alpha and beta subunits. {ECO:0000269|PubMed:17557808}.
Tissue SpecificityMostly expressed in seeds, and, to a lower extent, in roots, leaves (veins and trichomes), inflorescences, siliques, pollen (grains and tubes) and flowers (sepals and petals). {ECO:0000269|PubMed:17557808, ECO:0000269|PubMed:17892448}.