LMPD Database

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LMP010556

UniProt Annotations

Entry Information
Gene Namelipoxygenase 4
Protein EntryLOX4_ARATH
UniProt IDQ9FNX8
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityAlpha-linolenate + O(2) = (9Z,11E,13S,15Z)-13- hydroperoxyoctadeca-9,11,15-trienoate.
Catalytic ActivityLinoleate + O(2) = (9Z,11E,13S)-13- hydroperoxyoctadeca-9,11-dienoate.
CofactorName=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000255|PROSITE-ProRule:PRU00726}; Note=Binds 1 Fe cation per subunit. {ECO:0000255|PROSITE- ProRule:PRU00726};
Developmental StageExpression is greatly increased in leaves during leaf senescence. {ECO:0000269|PubMed:11891244}.
FunctionPlant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity). 13S-lipoxygenase that can use linolenic acid as substrates. {ECO:0000255|PROSITE- ProRule:PRU00726, ECO:0000269|PubMed:18949503}.
InductionInduced by bacterial pathogens (e.g. Pseudomonas syringae pv. tomato), ozone O(3), and wounding. {ECO:0000269|PubMed:12609040, ECO:0000269|PubMed:19054359}.
PathwayLipid metabolism; oxylipin biosynthesis. {ECO:0000255|PROSITE-ProRule:PRU00726}.
SimilarityBelongs to the lipoxygenase family. {ECO:0000305}.
SimilarityContains 1 lipoxygenase domain. {ECO:0000255|PROSITE- ProRule:PRU00726}.
SimilarityContains 1 PLAT domain. {ECO:0000255|PROSITE- ProRule:PRU00152}.
Subcellular LocationPlastid, chloroplast {ECO:0000305}.
Tissue SpecificityExpressed in leaves. {ECO:0000269|PubMed:17369372}.