LMPD Database

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LMP010544

UniProt Annotations

Entry Information
Gene Namelipid phosphate phosphatase 2
Protein EntryLPP2_ARATH
UniProt IDQ9XI60
SpeciesArabidopsis
Comments
Comment typeDescription
Disruption PhenotypeNo visible phenotype under normal growth conditions, but mutant plants show hypersensitivity to ABA and significant PA accumulation during seed germination. {ECO:0000269|PubMed:15960620}.
Enzyme RegulationPA phosphatase activity not inhibited by N- ethylmaleimide. {ECO:0000269|PubMed:11278556}.
FunctionMay play a general "housekeeping role" in lipid metabolism. Exhibits both diacylglycerol pyrophosphate (DGPP) phosphatase and phosphatidate (PA) phosphatase activities with no preference for either substrate. May play a role downstream of the ABA signaling pathway during seed germination and in stomatal movement in leaves. {ECO:0000269|PubMed:11278556, ECO:0000269|PubMed:15960620, ECO:0000269|PubMed:21277215}.
InductionConstitutively expressed. Not induced by stress, mastoparan or hypersensitive response elicitor harpin. Down- regulated by ABA. {ECO:0000269|PubMed:11278556, ECO:0000269|PubMed:21277215}.
SimilarityBelongs to the PA-phosphatase related phosphoesterase family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue SpecificityExpressed in roots, stems, leaves, buds, flowers and siliques. {ECO:0000269|PubMed:11278556, ECO:0000269|PubMed:15960620}.