LMPD Database

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LMP010543

UniProt Annotations

Entry Information
Gene Namelipid phosphate phosphatase 1
Protein EntryLPP1_ARATH
UniProt IDQ9ZU49
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9ZU49-1; Sequence=Displayed; Name=2; IsoId=Q9ZU49-2; Sequence=VSP_053601; Note=No experimental confirmation available.;
Enzyme RegulationPA phosphatase activity inhibited by N- ethylmaleimide with an IC(50) value of 10 mM. {ECO:0000269|PubMed:11278556}.
FunctionPlays a general role in cellular responses to stress, may be by attenuating the signal produced by phospholipases. Exhibits both diacylglycerol pyrophosphate (DGPP) phosphatase and phosphatidate (PA) phosphatase activities. Substrate preference is diacylglycerol pyrophosphate > phosphatidate. {ECO:0000269|PubMed:11278556}.
InductionRapid increase in response to severe radiation stress (gamma rays or UV-B). Returns to basal level 45 min after the radiation injury. Also induced by mastoparan and by the hypersensitive response elicitor harpin. In this later case, induction is also observed in the leaves adjacent to those that were infiltrated with harpin. {ECO:0000269|PubMed:11278556}.
Sequence CautionSequence=BX819931; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
SimilarityBelongs to the PA-phosphatase related phosphoesterase family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue SpecificityStrongly expressed in leaves, moderately in roots, weakly in floral hamps and flower buds, and not detected in adult flowers and seedpods. {ECO:0000269|PubMed:11278556}.