LMPD Database

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LMP010536

UniProt Annotations

Entry Information
Gene Namelipoxygenase 5
Protein EntryLOX5_ARATH
UniProt IDQ9LUW0
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityLinoleate + O(2) = (9S,10E,12Z)-9-hydroperoxy- 10,12-octadecadienoate.
CofactorName=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000255|PROSITE-ProRule:PRU00726}; Note=Binds 1 Fe cation per subunit. {ECO:0000255|PROSITE- ProRule:PRU00726};
Developmental StageFirst observed in lateral root primordia (LRP), from the first pericycle divisions. Disappears before root emergence. {ECO:0000269|PubMed:17369372}.
Disruption PhenotypeIncrement in the number of lateral roots, and moderate increase in the length of the primary root. {ECO:0000269|PubMed:17369372}.
Function9S-lipoxygenase that can use linoleic acid or linolenic acid as substrates. Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure. Function as regulators of root development by controlling the emergence of lateral roots. {ECO:0000269|PubMed:17369372, ECO:0000269|PubMed:18949503}.
PathwayLipid metabolism; oxylipin biosynthesis. {ECO:0000255|PROSITE-ProRule:PRU00726}.
Sequence CautionSequence=BAB01777.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the lipoxygenase family. {ECO:0000305}.
SimilarityContains 1 lipoxygenase domain. {ECO:0000255|PROSITE- ProRule:PRU00726}.
SimilarityContains 1 PLAT domain. {ECO:0000255|PROSITE- ProRule:PRU00152}.
Subcellular LocationPlastid, chloroplast {ECO:0000269|PubMed:15028209}.
Tissue SpecificityExpressed in roots. {ECO:0000269|PubMed:17369372}.