LMPD Database

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LMP010525

UniProt Annotations

Entry Information
Gene Nameceramide synthase LAG1
Protein EntryLAG13_ARATH
UniProt IDQ6NQI8
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6NQI8-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=2; IsoId=Q6NQI8-2; Sequence=VSP_013449, VSP_013450; Note=May be due to intron retention. No experimental confirmation available.;
FunctionMediates resistance to sphinganine-analog mycotoxins (SAMs) by restoring the sphingolipid biosynthesis. Could salvage the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi apparatus in ceramides-depleted cells after SAM exposure (By similarity). {ECO:0000250}.
SimilarityContains 1 TLC (TRAM/LAG1/CLN8) domain. {ECO:0000255|PROSITE-ProRule:PRU00205}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.