LMPD Database

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LMP010155

UniProt Annotations

Entry Information
Gene Namedolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit
Protein EntryOST48_ARATH
UniProt IDQ944K2
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityDolichyl diphosphooligosaccharide + [protein]- L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
Disruption PhenotypeEmbryo-lethal. {ECO:0000269|PubMed:15860005}.
FunctionEssential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. {ECO:0000269|PubMed:15860005}.
PathwayProtein modification; protein glycosylation.
Sequence CautionSequence=BAA97274.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the DDOST 48 kDa subunit family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
SubunitComponent of the oligosaccharyltransferase (OST) complex. {ECO:0000250}.