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LMPD Database

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LMP009026

UniProt Annotations

Entry Information

Gene Name	Lipid storage droplet-2
Protein Entry	Q0KHS7_DROME
UniProt ID	X2JKC1
Species	Drosophila

Comments

Comment type	Description
Developmental Stage	Expressed both maternally and zygotically. Expressed throughout development with highest zygotic expression in third instar larva and pupae. {ECO:0000269\|PubMed:12676093, ECO:0000269\|PubMed:14550535}.
Function	Essential for embryogenesis. Required for normal deposition of neutral lipids in the oocyte. {ECO:0000269\|PubMed:12676093, ECO:0000269\|PubMed:14550535}.
Similarity	Belongs to the perilipin family. {ECO:0000305}.
Subcellular Location	Cytoplasm. Lipid droplet. Note=Cytoplasm and on surface of neutral lipid storage droplets in oocytes. Colocalizes with Lsd-1 to the droplet surface in cells of fat bodies.
Tissue Specificity	Ubiquitous expression in early embryos. At stage 5 expression is restricted to the pole cells. At stage 11 expression is seen in the amnioserosa, refined to the fat body and midgut by stage 14. Also seen in the hindgut by the end of embryogenesis. Expression is seen in larval fat body (at protein level). {ECO:0000269\|PubMed:12676093, ECO:0000269\|PubMed:14550535}.