LMPD Database

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LMP008890

UniProt Annotations

Entry Information
Gene NameOligosaccharyltransferase 48kD subunit
Protein EntryOST48_DROME
UniProt IDQ24319
SpeciesDrosophila
Comments
Comment typeDescription
Catalytic ActivityDolichyl diphosphooligosaccharide + [protein]- L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
FunctionEssential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the DDOST 48 kDa subunit family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
SubunitComponent of the oligosaccharyltransferase (OST) complex. {ECO:0000250}.