LMPD Database

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LMP008875

UniProt Annotations

Entry Information
Gene NameCytochrome P450-18a1
Protein EntryCP18A_DROME
UniProt IDQ95078
SpeciesDrosophila
Comments
Comment typeDescription
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Developmental StageLow levels throughout postembryonic development.
FunctionProbably involved in steroid hormones biosynthesis. {ECO:0000269|PubMed:9256362}.
InductionBy 20-hydroxyecdysone during the three larval stages, at pupariation and in pupae. {ECO:0000269|PubMed:9256362}.
SimilarityBelongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue SpecificityExpressed in body wall (epidermal and muscle cells) and mid-and hind-gut. {ECO:0000269|PubMed:9256362}.