LMPD Database

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LMP008844

UniProt Annotations

Entry Information
Gene Namebrainiac
Protein EntryQ24157_DROME
UniProt IDQ24157
SpeciesDrosophila
Comments
Comment typeDescription
Catalytic ActivityUDP-alpha-D-galactose + an N-acetyl-beta-D- galactosaminyl-(1->4)-(alpha-N-acetylneuraminyl-(2->3))-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + a beta- D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-(alpha- N-acetylneuraminyl-(2->3))-beta-D-galactosyl-(1->4)-beta-D- glucosyl-(1<->1)-ceramide.
FunctionNeurogenic protein essential for the development and maintenance of epithelial structure. Required in the germline for establishing the follicular epithelium and for determining the dorsal-ventral polarity. Collaborates with Notch on the apical surface of follicle cells to mediate germline-follicle cell adhesion. Brn has a role in chorion formation.
Sequence CautionSequence=AAL48007.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the glycosyltransferase 31 family.
Subcellular LocationGolgi apparatus membrane ; Single-pass type II membrane protein .