LMPD Database

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LMP007847

UniProt Annotations

Entry Information
Gene NameProtein ASAH-1
Protein EntryASAH1_CAEEL
UniProt IDO45686
SpeciesC. elegans
Comments
Comment typeDescription
Catalytic ActivityN-acylsphingosine + H(2)O = a carboxylate + sphingosine.
FunctionHydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. {ECO:0000250}.
InteractionQ9TYY1:lag-1; NbExp=1; IntAct=EBI-324508, EBI-324482; Q9XUQ4:vps-39; NbExp=1; IntAct=EBI-324508, EBI-318975;
PathwayLipid metabolism; sphingolipid metabolism.
SimilarityBelongs to the acid ceramidase family. {ECO:0000305}.
Subcellular LocationLysosome {ECO:0000250}.
SubunitHeterodimer of one alpha and one beta subunit. {ECO:0000250}.