LMPD Database

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LMP007828

UniProt Annotations

Entry Information
Gene NameProtein FAT-3
Protein EntryFAT3_CAEEL
UniProt IDQ23221
SpeciesC. elegans
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=a; IsoId=Q23221-1; Sequence=Displayed; Name=b; IsoId=Q23221-2; Sequence=VSP_047787; Name=c; IsoId=Q23221-3; Sequence=VSP_047786;
FunctionDelta(6) fatty acid desaturase that acts on a range of substrates. Catalyzes the desaturation of linoleic acid (Delta(9,12)-18:2, or C18:2(n-6)) to gamma-linolenic acid (Delta(6,9,12)-18:3, or C18:3(n-6)). {ECO:0000269|PubMed:11972048, ECO:0000269|PubMed:9480865}.
PathwayLipid metabolism; polyunsaturated fatty acid biosynthesis. {ECO:0000269|PubMed:11972048, ECO:0000269|PubMed:9480865}.
SimilarityBelongs to the fatty acid desaturase family. {ECO:0000305}.
SimilarityContains 1 cytochrome b5 heme-binding domain. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.