LMPD Database

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LMP007749

UniProt Annotations

Entry Information
Gene Nameundecaprenyl phosphate-L-Ara4FN transferase
Protein EntryARNC_ECOLI
UniProt IDP77757
SpeciesE. coli
Comments
Comment typeDescription
Catalytic ActivityUDP-4-deoxy-4-formamido-beta-L-arabinose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4- formamido-alpha-L-arabinose ditrans,octacis-undecaprenyl phosphate. {ECO:0000269|PubMed:15695810}.
FunctionCatalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. {ECO:0000269|PubMed:11706007}.
InductionInduced by BasR. {ECO:0000250}.
PathwayBacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. {ECO:0000269|PubMed:17928292}.
PathwayGlycolipid biosynthesis; 4-amino-4-deoxy-alpha-L- arabinose undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy- alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4- formamido-beta-L-arabinose and undecaprenyl phosphate: step 1/2. {ECO:0000269|PubMed:17928292}.
SimilarityBelongs to the glycosyltransferase 2 family. {ECO:0000305}.
Subcellular LocationCell inner membrane; Multi-pass membrane protein.