LMPD Database

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LMP007651

UniProt Annotations

Entry Information
Gene Nameperiplasmic glycerophosphodiester phosphodiesterase
Protein EntryGLPQ_ECOLI
UniProt IDP09394
SpeciesE. coli
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=0.28 mM for glycerophosphocholine {ECO:0000269|PubMed:2829735}; KM=0.24 mM for glycerophosphoethanolamine {ECO:0000269|PubMed:2829735}; KM=0.35 mM for glycerophosphoglycerol {ECO:0000269|PubMed:2829735}; KM=0.59 mM for glycerophosphoserine {ECO:0000269|PubMed:2829735}; KM=1.0 mM for glycerophosphoinositol {ECO:0000269|PubMed:2829735}; pH dependence: Optimum pH is 7.8. {ECO:0000269|PubMed:2829735};
Catalytic ActivityA glycerophosphodiester + H(2)O = an alcohol + sn-glycerol 3-phosphate. {ECO:0000269|PubMed:2829735}.
CofactorName=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000269|PubMed:2829735}; Note=Binds 1 Ca(2+) ion per subunit. {ECO:0000269|PubMed:2829735};
FunctionGlycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.
MiscellaneousThere are 2 isozymes of glycerophosphoryl diester phosphodiesterase in E.coli: a periplasmic isozyme (GlpQ) and a cytosolic isozyme (UgpQ).
SimilarityBelongs to the glycerophosphoryl diester phosphodiesterase family. {ECO:0000305}.
SimilarityContains 1 GP-PDE domain. {ECO:0000305}.
Subcellular LocationPeriplasm {ECO:0000269|PubMed:2829735}.
SubunitHomodimer. {ECO:0000269|PubMed:2829735, ECO:0000269|Ref.10, ECO:0000269|Ref.9}.