LMPD Database

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LMP007571

UniProt Annotations

Entry Information
Gene NameUDP-N-acetylglucosamine acetyltransferase
Protein EntryLPXA_ECOLI
UniProt IDP0A722
SpeciesE. coli
Comments
Comment typeDescription
Catalytic Activity(R)-3-hydroxytetradecanoyl-[acyl-carrier- protein] + UDP-N-acetyl-alpha-D-glucosamine = [acyl-carrier- protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetyl-alpha-D- glucosamine. {ECO:0000255|HAMAP-Rule:MF_00387}.
FunctionInvolved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
PathwayGlycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. {ECO:0000255|HAMAP- Rule:MF_00387}.
SimilarityBelongs to the transferase hexapeptide repeat family. LpxA subfamily. {ECO:0000255|HAMAP-Rule:MF_00387}.
Subcellular LocationCytoplasm.
SubunitHomotrimer. {ECO:0000255|HAMAP-Rule:MF_00387, ECO:0000269|PubMed:16835299, ECO:0000269|PubMed:17434525, ECO:0000269|PubMed:17698807}.