LMPD Database

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LMP007522

UniProt Annotations

Entry Information
Gene Namebifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1
Protein EntryGPT1_YEAST
UniProt IDP32784
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate.
Catalytic ActivityAcyl-CoA + sn-glycerol 3-phosphate = CoA + 1- acyl-sn-glycerol 3-phosphate.
DomainThe HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}.
FunctionG-3-P/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase. {ECO:0000269|PubMed:11544256}.
MiscellaneousPresent with 1050 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayPhospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.
SimilarityBelongs to the GPAT/DAPAT family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.