LMPD Database

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LMP007361

UniProt Annotations

Entry Information
Gene NamePlb1p
Protein EntryPLB1_YEAST
UniProt IDP39105
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic Activity2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate.
FunctionSequentially removes both fatty acyl groups from diacylglycerophospholipids and therefore has both phospholipase A and lysophospholipase activities. Substrate preference is phosphatidylserine > phosphatidylinositol >> phosphatidylcholine > phosphatidylethanolamine. {ECO:0000269|PubMed:10497163, ECO:0000269|PubMed:8051052}.
InteractionP38800:YHR080C; NbExp=1; IntAct=EBI-13462, EBI-24597;
SimilarityBelongs to the lysophospholipase family
SimilarityBelongs to the lysophospholipase family. {ECO:0000305}.
SimilarityContains 1 PLA2c domain. {ECO:0000255|PROSITE- ProRule:PRU00555}.
Subcellular LocationCell membrane {ECO:0000305|PubMed:10383953, ECO:0000305|PubMed:10497163}; Lipid-anchor, GPI-anchor .
Subcellular LocationCell membrane {ECO:0000305|PubMed:10383953, ECO:0000305|PubMed:10497163}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:10383953, ECO:0000305|PubMed:10497163}.