LMPD Database

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LMP007154

UniProt Annotations

Entry Information
Gene Nameenoyl-CoA hydratase PHS1
Protein EntryPHS1_YEAST
UniProt IDP40857
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityA very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain trans-2,3-dehydroacyl-CoA + H(2)O. {ECO:0000269|PubMed:17719544, ECO:0000269|PubMed:18272525}.
FunctionResponsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis. {ECO:0000269|PubMed:17719544, ECO:0000269|PubMed:18272525}.
SimilarityBelongs to the very long-chain fatty acids dehydratase HACD family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.