Comment type | Description |
Catalytic Activity | A 1,2-diacylglycerol 3-phosphate + H(2)O = a 1,2-diacyl-sn-glycerol + phosphate |
Catalytic Activity | A 1,2-diacylglycerol 3-phosphate + H(2)O = a 1,2-diacyl-sn-glycerol + phosphate. {ECO:0000269|PubMed:23071111}. |
Cofactor | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence= ; |
Cofactor | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; |
Domain | Contains one Asp-Xaa-Asp-Xaa-Thr (DXDXT) motif, a catalytic motif essential for phosphatidate phosphatase activity. |
Enzyme Regulation | Inhibited by N-ethylmaleimide |
Enzyme Regulation | Inhibited by N-ethylmaleimide. {ECO:0000269|PubMed:23071111}. |
Function | Mg(2+)-dependent phosphatidate (PA) phosphatase which catalyzes the dephosphorylation of PA to yield diacylglycerol. May play a role in vesicular trafficking through its PAP activity at cortical actin patches |
Function | Mg(2+)-dependent phosphatidate (PA) phosphatase which catalyzes the dephosphorylation of PA to yield diacylglycerol. May play a role in vesicular trafficking through its PAP activity at cortical actin patches. {ECO:0000269|PubMed:23071111}. |
Interaction | P15891:ABP1; NbExp=9; IntAct=EBI-28798, EBI-2036; P47068:BBC1; NbExp=3; IntAct=EBI-28798, EBI-3437; P38822:BZZ1; NbExp=14; IntAct=EBI-28798, EBI-3889; Q05080:HOF1; NbExp=2; IntAct=EBI-28798, EBI-5412; P53281:LSB1; NbExp=4; IntAct=EBI-28798, EBI-23329; P43603:LSB3; NbExp=8; IntAct=EBI-28798, EBI-22980; Q04439:MYO5; NbExp=2; IntAct=EBI-28798, EBI-11687; P80667:PEX13; NbExp=2; IntAct=EBI-28798, EBI-13206; Q06449:PIN3; NbExp=4; IntAct=EBI-28798, EBI-35523; P39743:RVS167; NbExp=9; IntAct=EBI-28798, EBI-14500; P32790:SLA1; NbExp=4; IntAct=EBI-28798, EBI-17313; P32793:YSC84; NbExp=6; IntAct=EBI-28798, EBI-24460; |
Miscellaneous | Present with 2289 molecules/cell in log phase SD medium |
Miscellaneous | Present with 2289 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
Ptm | N-glycosylated |
Ptm | N-glycosylated. {ECO:0000269|PubMed:19756047}. |
Sequence Caution | Sequence=CAA59823.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ; |
Sequence Caution | Sequence=CAA59823.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; |
Subcellular Location | Cytoplasm, cytoskeleton, actin patch . |
Subcellular Location | Cytoplasm, cytoskeleton, actin patch {ECO:0000269|PubMed:11489916, ECO:0000269|PubMed:14562095}. |
Subunit | Interacts with ABP1 |
Subunit | Interacts with ABP1. {ECO:0000269|PubMed:14737190}. |