LMPD Database

LMP007018

UniProt Annotations

Entry Information
Gene Namesuccinate dehydrogenase cytochrome b subunit SDH3
Protein EntrySDH3_YEAST
UniProt IDP33421
SpeciesYeast (S288c)
Comments
Comment typeDescription
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Note=The heme is bound between the two transmembrane subunits.;
FunctionMembrane-anchoring mono-heme cytochrome b subunit of succinate dehydrogenase (SDH) that is involved in system II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH3 and SDH4 form the membrane dimer that anchors the catalytic dimer formed by SDH1 and SDH2 to the matrix surface of the mitochondrial inner membrane. Electrons originating from the catalytic dimer enter the membrane dimer for ubiquinone reduction.
MiscellaneousPresent with 238 molecules/cell in log phase SD medium
MiscellaneousPresent with 238 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayCarbohydrate metabolism; tricarboxylic acid cycle.
SimilarityBelongs to the cytochrome b560 family
SimilarityBelongs to the cytochrome b560 family. {ECO:0000305}.
Subcellular LocationMitochondrion inner membrane; Multi-pass membrane protein.
SubunitForms part of complex II containing four subunits: a flavoprotein (FP), an iron-sulfur protein (IP) and a cytochrome b composed of two integral membrane proteins.