LMPD Database

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LMP006913

UniProt Annotations

Entry Information
Gene Nametype 2C protein phosphatase PTC2
Protein EntryPP2C2_YEAST
UniProt IDP39966
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic Activity[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=Binds 2 magnesium or manganese ions per subunit. {ECO:0000250};
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence= ; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence= ; Note=Binds 2 magnesium or manganese ions per subunit. ;
FunctionResponsible, together with PTC3, for the dephosphorylation of the cyclin-dependent protein kinase CDC28
FunctionResponsible, together with PTC3, for the dephosphorylation of the cyclin-dependent protein kinase CDC28. {ECO:0000269|PubMed:10580002}.
InteractionQ12447:PAA1; NbExp=7; IntAct=EBI-12795, EBI-33397;
MiscellaneousPresent with 12600 molecules/cell in log phase SD medium
MiscellaneousPresent with 12600 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the PP2C family
SimilarityBelongs to the PP2C family. {ECO:0000305}.