LMPD Database

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LMP006912

UniProt Annotations

Entry Information
Gene NameIrs4p
Protein EntryIRS4_YEAST
UniProt IDP36115
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionWith TAX4, acts as a positive regulator of INP51 activity and phosphatidylinositol 4,5-bisphosphate turnover. Negatively regulates signaling through the cell integrity pathway, including the MAP kinase SLT2. Seems also to be involved in rDNA silencing. {ECO:0000269|PubMed:10082585, ECO:0000269|PubMed:15265867}.
InteractionP40559:INP51; NbExp=3; IntAct=EBI-27090, EBI-24915;
SimilarityBelongs to the IRS4 family
SimilarityBelongs to the IRS4 family. {ECO:0000305}.
SimilarityContains 1 EH domain
SimilarityContains 1 EH domain. {ECO:0000305}.
SubunitInteracts with INP51
SubunitInteracts with INP51. {ECO:0000269|PubMed:15265867}.