LMPD Database

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LMP006909

UniProt Annotations

Entry Information
Gene Nameacetolactate synthase regulatory subunit
Protein EntryILV6_YEAST
UniProt IDP25605
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionStimulates activity of the acetolactate synthase catalytic subunit ILV2 seven- to tenfold and confers sensitivity to inhibition by valine and activation by ATP
FunctionStimulates activity of the acetolactate synthase catalytic subunit ILV2 seven- to tenfold and confers sensitivity to inhibition by valine and activation by ATP. {ECO:0000269|PubMed:10213630}.
InteractionSelf; NbExp=1; IntAct=EBI-9087, EBI-9087; P10592:SSA2; NbExp=1; IntAct=EBI-9087, EBI-8603;
MiscellaneousPresent with 15800 molecules/cell in log phase SD medium
MiscellaneousPresent with 15800 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayAmino-acid biosynthesis; L-isoleucine biosynthesis; L- isoleucine from 2-oxobutanoate: step 1/4.
PathwayAmino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.
SimilarityBelongs to the acetolactate synthase small subunit family
SimilarityBelongs to the acetolactate synthase small subunit family. {ECO:0000305}.
SimilarityContains 1 ACT domain. {ECO:0000255|PROSITE- ProRule:PRU01007}.
Subcellular LocationMitochondrion.
SubunitThe acetolactate synthase complex contains the catalytic regulatory subunit ILV2 and the regulatory small subunit ILV6.