LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP006879

UniProt Annotations

Entry Information
Gene Nameglutamine--fructose-6-phosphate transaminase (isomerizing) GFA1
Protein EntryGFA1_YEAST
UniProt IDP14742
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityL-glutamine + D-fructose 6-phosphate = L- glutamate + D-glucosamine 6-phosphate. {ECO:0000269|PubMed:15699032}.
FunctionInvolved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins). {ECO:0000269|PubMed:15699032}.
InductionThe activity of this enzyme increases in presence of mating pheromone (transcriptional regulation).
MiscellaneousPresent with 14300 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayNucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D- glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D- fructose 6-phosphate: step 1/1.
SimilarityContains 1 glutamine amidotransferase type-2 domain. {ECO:0000255|PROSITE-ProRule:PRU00609}.
SimilarityContains 2 SIS domains. {ECO:0000255|PROSITE- ProRule:PRU00797}.