LMPD Database

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LMP006862

UniProt Annotations

Entry Information
Gene NameSte14p
Protein EntrySTE14_YEAST
UniProt IDP32584
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityS-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C- terminal S-farnesyl-L-cysteine methyl ester.
FunctionMediates C-terminal methylation of the isoprenylated C- terminal cysteine in A-factor mating pheromone and Ras proteins. {ECO:0000269|PubMed:8289819}.
MiscellaneousPresent with 2690 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.