LMPD Database

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LMP006838

UniProt Annotations

Entry Information
Gene Namedihydroxy-acid dehydratase ILV3
Protein EntryILV3_YEAST
UniProt IDP39522
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic Activity2,3-dihydroxy-3-methylbutanoate = 3-methyl-2- oxobutanoate + H(2)O.
CofactorName=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000305}; Note=Binds 1 [4Fe-4S] cluster. {ECO:0000305};
CofactorName=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence= ; Note=Binds 1 [4Fe-4S] cluster. ;
MiscellaneousPresent with 171000 molecules/cell in log phase SD medium
MiscellaneousPresent with 171000 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
PathwayAmino-acid biosynthesis; L-isoleucine biosynthesis; L- isoleucine from 2-oxobutanoate: step 3/4.
PathwayAmino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.
SimilarityBelongs to the IlvD/Edd family
SimilarityBelongs to the IlvD/Edd family. {ECO:0000305}.
Subcellular LocationMitochondrion.
SubunitHomodimer.