LMPD Database

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LMP006749

UniProt Annotations

Entry Information
Gene Namehydroxysteroid (17-beta) dehydrogenase 14
Protein EntryDHB14_HUMAN
UniProt IDQ9BPX1
SpeciesHuman
Comments
Comment typeDescription
FunctionHas NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3- beta,17-beta-diol (in vitro).
InteractionQ6ZVK8:NUDT18; NbExp=3; IntAct=EBI-742664, EBI-740486; Q96HA8:WDYHV1; NbExp=3; IntAct=EBI-742664, EBI-741158;
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family.
Subcellular LocationCytoplasm .
SubunitHomotetramer.
Tissue SpecificityHighly expressed in brain, placenta, liver and kidney. {ECO