LMPD Database

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LMP006740

UniProt Annotations

Entry Information
Gene Namephosphatidylinositol glycan anchor biosynthesis, class G
Protein EntryPIGG_HUMAN
UniProt IDQ8NCI4
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=6; Name=1; IsoId=Q5H8A4-1; Sequence=Displayed; Name=2; IsoId=Q5H8A4-2; Sequence=VSP_019832; Note=No experimental confirmation available.; Name=3; IsoId=Q5H8A4-3; Sequence=VSP_019828; Note=No experimental confirmation available.; Name=4; IsoId=Q5H8A4-4; Sequence=VSP_019831, VSP_019833; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; Name=5; IsoId=Q5H8A4-5; Sequence=VSP_019827, VSP_019829, VSP_019830; Note=No experimental confirmation available.; Name=6; IsoId=Q5H8A4-6; Sequence=VSP_054387, VSP_054388, VSP_019833; Note=No experimental confirmation available.;
FunctionEthanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Sequence CautionSequence=AAQ88902.1; Type=Erroneous termination; Positions=311; Note=Translated as Gln.; Evidence= ; Sequence=BAA91046.1; Type=Erroneous initiation; Evidence= ; Sequence=BAB55130.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
Subcellular LocationEndoplasmic reticulum membrane ; Multi-pass membrane protein .
SubunitForms a complex with PIGF. PIGF is required to stabilize it. Competes with PIGO for the binding of PIGF.