LMPD Database

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LMP006579

UniProt Annotations

Entry Information
Gene Namehexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
Protein EntryHEXDC_MOUSE
UniProt IDQ3U4H6
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q3U4H6-1; Sequence=Displayed; Name=2; IsoId=Q3U4H6-2; Sequence=VSP_030778; Note=No experimental confirmation available.;
Biophysicochemical PropertiesKinetic parameters: KM=0.25 mM for p-nitrophenyl-beta-N-acetylgalactosaminide {ECO:0000269|PubMed:19040401}; pH dependence: Optimum pH is 5.5. {ECO:0000269|PubMed:19040401}; Temperature dependence: Optimum temperature is 37 degrees Celsius. {ECO:0000269|PubMed:19040401};
Catalytic ActivityHydrolysis of terminal non-reducing N-acetyl- D-hexosamine residues in N-acetyl-beta-D-hexosaminides. {ECO:0000269|PubMed:19040401}.
Enzyme RegulationInhibited by O-(2-acetamido-2-deoxy-D- glucopyranosylidene)amino N-phenylcarbamate (PUGNAc). {ECO:0000269|PubMed:19040401}.
FunctionHas hexosaminidase activity. {ECO:0000269|PubMed:19040401}.
Sequence CautionSequence=AAH69960.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the glycosyl hydrolase 20 family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:19040401}. Nucleus {ECO:0000269|PubMed:19040401}.
SubunitHomodimer; disulfide-linked. {ECO:0000269|PubMed:19040401}.
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:19040401}.