LMPD Database

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LMP006557

Gene Information

Entrez Gene ID16331
Gene Nameinositol polyphosphate-5-phosphatase D
Gene SymbolInpp5d
SpeciesMus musculus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IEA:UniProtKB-KWCcytoplasm
GO:0005886 IEA:UniProtKB-KWCplasma membrane
GO:0004445 IDA:MGIFinositol-polyphosphate 5-phosphatase activity
GO:0034594 IDA:MGIFphosphatidylinositol trisphosphate phosphatase activity
GO:0051425 IDA:MGIFPTB domain binding
GO:0017124 IDA:MGIFSH3 domain binding
GO:0006915 IEA:UniProtKB-KWPapoptotic process
GO:0016311 IDA:GOCPdephosphorylation
GO:0008340 IMP:MGIPdetermination of adult lifespan
GO:0016064 IMP:MGIPimmunoglobulin mediated immune response
GO:0035556 IMP:MGIPintracellular signal transduction
GO:0050869 IMP:MGIPnegative regulation of B cell activation
GO:0030889 IMP:MGIPnegative regulation of B cell proliferation
GO:0045779 IMP:MGIPnegative regulation of bone resorption
GO:0008285 IDA:MGIPnegative regulation of cell proliferation
GO:0030853 IMP:MGIPnegative regulation of granulocyte differentiation
GO:0050777 IMP:MGIPnegative regulation of immune response
GO:0045409 IMP:MGIPnegative regulation of interleukin-6 biosynthetic process
GO:0045656 IMP:MGIPnegative regulation of monocyte differentiation
GO:0045659 IMP:MGIPnegative regulation of neutrophil differentiation
GO:0045671 IMP:MGIPnegative regulation of osteoclast differentiation
GO:0009968 IMP:MGIPnegative regulation of signal transduction
GO:0046856 IEA:InterProPphosphatidylinositol dephosphorylation
GO:0043065 IMP:MGIPpositive regulation of apoptotic process
GO:0045579 IMP:MGIPpositive regulation of B cell differentiation
GO:0045648 IMP:MGIPpositive regulation of erythrocyte differentiation
GO:0045621 IMP:MGIPpositive regulation of lymphocyte differentiation
KEGG Pathway Links
KEGG Pathway IDDescription
ko04662B cell receptor signaling pathway
mmu04662B cell receptor signaling pathway
ko04664Fc epsilon RI signaling pathway
mmu04664Fc epsilon RI signaling pathway
ko04666Fc gamma R-mediated phagocytosis
mmu04666Fc gamma R-mediated phagocytosis
ko00562Inositol phosphate metabolism
mmu00562Inositol phosphate metabolism
ko04070Phosphatidylinositol signaling system
mmu04070Phosphatidylinositol signaling system
BIOCYC Pathway Links
BIOCYC Pathway IDDescription
PWY-6363D-myo-inositol (1,4,5)-trisphosphate degradation
PWY-6358superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism
REACTOME Pathway Links
REACTOME Pathway IDDescription
5892925Adaptive Immune System
5893046Cytokine Signaling in Immune system
5893545Downstream TCR signaling
5892920Immune System
5894026Inositol phosphate metabolism
5893044Interleukin-2 signaling
5893511Interleukin-3, 5 and GM-CSF signaling
5893510Interleukin receptor SHC signaling
5892760Metabolism
5892799Metabolism of lipids and lipoproteins
5892984Phospholipid metabolism
5893988PI Metabolism
5893045Signaling by Interleukins
5894025Synthesis of IP3 and IP4 in the cytosol
5894009Synthesis of PIPs at the plasma membrane
5893546TCR signaling