LMPD Database

LMP006488

Gene Information

Entrez Gene ID	653361
Gene Name	neutrophil cytosolic factor 1
Gene Symbol	NCF1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	IDA:UniProtKB	C	cytosol
GO:0030425	IEA:Ensembl	C	dendrite
GO:0019898	IDA:UniProtKB	C	extrinsic component of membrane
GO:0005794	IEA:Ensembl	C	Golgi apparatus
GO:0043020	IDA:UniProtKB	C	NADPH oxidase complex
GO:0043025	IEA:Ensembl	C	neuronal cell body
GO:0032010	TAS:Reactome	C	phagolysosome
GO:0005791	IEA:Ensembl	C	rough endoplasmic reticulum
GO:0009055	TAS:UniProtKB	F	electron carrier activity
GO:0043325	IDA:UniProtKB	F	phosphatidylinositol-3,4-bisphosphate binding
GO:0035091	IDA:UniProtKB	F	phosphatidylinositol binding
GO:0017124	IPI:BHF-UCL	F	SH3 domain binding
GO:0016175	IMP:UniProtKB	F	superoxide-generating NADPH oxidase activity
GO:0042590	TAS:Reactome	P	antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479	TAS:Reactome	P	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474	TAS:Reactome	P	antigen processing and presentation of peptide antigen via MHC class I
GO:0006915	IEA:Ensembl	P	apoptotic process
GO:0008283	IEA:Ensembl	P	cell proliferation
GO:0006968	TAS:ProtInc	P	cellular defense response
GO:0050665	IEA:Ensembl	P	hydrogen peroxide biosynthetic process
GO:0006954	IEA:Ensembl	P	inflammatory response
GO:0045087	TAS:BHF-UCL	P	innate immune response
GO:0051701	TAS:Reactome	P	interaction with host
GO:0006691	IEA:Ensembl	P	leukotriene metabolic process
GO:0045986	IEA:Ensembl	P	negative regulation of smooth muscle contraction
GO:0070947	IEA:Ensembl	P	neutrophil mediated killing of fungus
GO:0070946	IEA:Ensembl	P	neutrophil mediated killing of gram-positive bacterium
GO:0055114	IMP:GOC	P	oxidation-reduction process
GO:0090382	TAS:Reactome	P	phagosome maturation
GO:0006612	IDA:UniProtKB	P	protein targeting to membrane
GO:0045730	TAS:BHF-UCL	P	respiratory burst
GO:0002679	IEA:Ensembl	P	respiratory burst involved in defense response
GO:0001878	IEA:Ensembl	P	response to yeast
GO:0042554	IMP:UniProtKB	P	superoxide anion generation
GO:0006801	TAS:BHF-UCL	P	superoxide metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa05140	Leishmaniasis
hsa04380	Osteoclast differentiation
hsa04145	Phagosome