LMPD Database

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LMP006373

UniProt Annotations

Entry Information
Gene Nameretinol dehydrogenase 7
Protein EntryRDH7_MOUSE
UniProt IDO88451
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAll-trans-retinol-[cellular-retinol-binding- protein] + NAD(+) = all-trans-retinal-[cellular-retinol-binding- protein] + NADH.
FunctionActs on androgens and retinols, i.e. has steroid 3- alpha- and 17-beta-dehydrogenase and cis/trans-retinol catalytic activities. {ECO:0000269|PubMed:9651397}.
PathwayCofactor metabolism; retinol metabolism.
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family. {ECO:0000305}.
Subcellular LocationMicrosome {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
Tissue SpecificityHighly expressed in liver. Also expressed in lung, eye, kidney, and brain. {ECO:0000269|PubMed:9651397}.