LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP006368

UniProt Annotations

Entry Information
Gene Nametransmembrane protein 55B
Protein EntryTM55B_HUMAN
UniProt IDQ86T03
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q86T03-1; Sequence=Displayed; Name=2; IsoId=Q86T03-2; Sequence=VSP_007815; Note=No experimental confirmation available.; Name=3; IsoId=Q86T03-3; Sequence=VSP_007816, VSP_007817; Note=May be due to intron retention..;
Catalytic Activity1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.
Catalytic Activity1-phosphatidyl-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.
FunctionCatalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate.
Sequence CautionSequence=CAB70896.1; Type=Erroneous initiation; Evidence= ; Sequence=CAD62347.1; Type=Erroneous initiation; Evidence= ;
Subcellular LocationLate endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein .
Tissue SpecificityUbiquitous.