LMPD Database

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LMP006281

UniProt Annotations

Entry Information
Gene Namezinc finger, DHHC-type containing 15
Protein EntryZDH15_HUMAN
UniProt IDQ96MV8
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q96MV8-1; Sequence=Displayed; Name=2; IsoId=Q96MV8-2; Sequence=VSP_013206, VSP_013207, VSP_013208; Note=No experimental confirmation available.; Name=3; IsoId=Q96MV8-3; Sequence=VSP_013206; Note=No experimental confirmation available.;
Catalytic ActivityPalmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.
DiseaseMental retardation, X-linked 91 (MRX91) [MIM
DomainThe DHHC domain is required for palmitoyltransferase activity.
FunctionPalmitoyltransferase specific for GAP43 and DLG4/PSD95.
PtmAutopalmitoylated.
SimilarityBelongs to the DHHC palmitoyltransferase family.
SimilarityContains 1 DHHC-type zinc finger.
Subcellular LocationMembrane ; Multi-pass membrane protein .
Tissue SpecificityExpressed in placenta, liver, lung, kidney, heart and brain.