LMPD Database

LMP006274

Gene Information

Entrez Gene ID	10419
Gene Name	protein arginine methyltransferase 5
Gene Symbol	PRMT5
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:HPA	C	cytoplasm
GO:0005829	IDA:UniProtKB	C	cytosol
GO:0034709	IDA:UniProtKB	C	methylosome
GO:0005634	NAS:UniProtKB	C	nucleus
GO:0003682	IEA:Ensembl	F	chromatin binding
GO:0001046	ISS:UniProtKB	F	core promoter sequence-specific DNA binding
GO:0008469	IBA:RefGenome	F	histone-arginine N-methyltransferase activity
GO:0008168	IDA:MGI	F	methyltransferase activity
GO:0035243	IMP:UniProtKB	F	protein-arginine omega-N symmetric methyltransferase activity
GO:0043021	IPI:UniProtKB	F	ribonucleoprotein complex binding
GO:0003714	ISS:UniProtKB	F	transcription corepressor activity
GO:0008283	TAS:ProtInc	P	cell proliferation
GO:0032922	ISS:UniProtKB	P	circadian regulation of gene expression
GO:0042118	IMP:UniProtKB	P	endothelial cell activation
GO:0010467	TAS:Reactome	P	gene expression
GO:0043985	ISS:UniProtKB	P	histone H4-R3 methylation
GO:0034660	TAS:Reactome	P	ncRNA metabolic process
GO:0000122	IEA:Ensembl	P	negative regulation of transcription from RNA polymerase II promoter
GO:0018216	IMP:UniProtKB	P	peptidyl-arginine methylation
GO:0019918	IMP:GOC	P	peptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0035246	IDA:MGI	P	peptidyl-arginine N-methylation
GO:0007088	TAS:ProtInc	P	regulation of mitosis
GO:0006355	IBA:RefGenome	P	regulation of transcription, DNA-templated
GO:0016070	TAS:Reactome	P	RNA metabolic process
GO:0000387	IMP:UniProtKB	P	spliceosomal snRNP assembly
GO:0006351	IEA:UniProtKB-KW	P	transcription, DNA-templated

KEGG Pathway Links

KEGG Pathway ID	Description
hsa03013	RNA transport
ko03013	RNA transport

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_228108	RMTs methylate histone arginines
REACT_11066	snRNP Assembly