LMPD Database

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LMP006256

UniProt Annotations

Entry Information
Gene Nameaminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Protein EntryADPPT_MOUSE
UniProt IDQ9CQF6
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9CQF6-1; Sequence=Displayed; Name=2; IsoId=Q9CQF6-2; Sequence=VSP_016096; Note=No experimental confirmation available.;
Catalytic ActivityCoA-[4'-phosphopantetheine] + apo-[acyl- carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl- carrier-protein].
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion. {ECO:0000250};
FunctionCatalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'- phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN (in vitro) (By similarity). {ECO:0000250}.
SimilarityBelongs to the P-Pant transferase superfamily. AcpS family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000250}.
SubunitMonomer. Interacts with FASN (By similarity). {ECO:0000250}.