LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP005931

UniProt Annotations

Entry Information
Gene Namecrystallin, zeta
Protein EntryQOR_MOUSE
UniProt IDP47199
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityNADPH + 2 quinone = NADP(+) + 2 semiquinone.
FunctionDoes not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding (By similarity). {ECO:0000250}.
SimilarityBelongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000250}.
SubunitHomotetramer. {ECO:0000250}.