LMPD Database

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LMP005824

UniProt Annotations

Entry Information
Gene Nameprenyl (decaprenyl) diphosphate synthase, subunit 1
Protein EntryDPS1_HUMAN
UniProt IDQ5T2R2
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q5T2R2-1; Sequence=Displayed; Name=2; IsoId=Q5T2R2-2; Sequence=VSP_017101; Note=No experimental confirmation available.; Name=3; IsoId=Q5T2R2-3; Sequence=VSP_017100;
Catalytic Activity(2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate.
CofactorName=Mg(2+); Xref=ChEBI
DiseaseCoenzyme Q10 deficiency, primary, 2 (COQ10D2) [MIM
FunctionSupplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
PathwayCofactor biosynthesis; ubiquinone biosynthesis.
SimilarityBelongs to the FPP/GGPP synthase family.
Subcellular LocationMitochondrion .
SubunitHeterotetramer of 2 DPS1/TPRT and 2 DLP1 subunits.