LMPD Database

LMP005609

Gene Information

Entrez Gene ID	100017
Gene Name	low density lipoprotein receptor adaptor protein 1
Gene Symbol	Ldlrap1
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030121	IEA:Ensembl	C	AP-1 adaptor complex
GO:0030122	IEA:Ensembl	C	AP-2 adaptor complex
GO:0030424	IEA:Ensembl	C	axon
GO:0009925	ISS:UniProtKB	C	basal plasma membrane
GO:0005737	IDA:BHF-UCL	C	cytoplasm
GO:0009898	IEA:Ensembl	C	cytoplasmic side of plasma membrane
GO:0005829	ISS:UniProtKB	C	cytosol
GO:0005769	IDA:MGI	C	early endosome
GO:0005883	IDA:BHF-UCL	C	neurofilament
GO:0055037	IEA:Ensembl	C	recycling endosome
GO:0001540	IPI:BHF-UCL	F	beta-amyloid binding
GO:0030276	ISS:UniProtKB	F	clathrin binding
GO:0005546	IEA:Ensembl	F	phosphatidylinositol-4,5-bisphosphate binding
GO:0001784	ISS:UniProtKB	F	phosphotyrosine binding
GO:0005102	ISA:MGI	F	receptor binding
GO:0035591	IEA:Ensembl	F	signaling adaptor activity
GO:0042982	IEA:Ensembl	P	amyloid precursor protein metabolic process
GO:0042632	IMP:MGI	P	cholesterol homeostasis
GO:0008203	IEA:UniProtKB-KW	P	cholesterol metabolic process
GO:0048260	ISS:UniProtKB	P	positive regulation of receptor-mediated endocytosis
GO:0031623	IEA:Ensembl	P	receptor internalization
GO:0090118	IEA:Ensembl	P	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
GO:0090003	IEA:Ensembl	P	regulation of establishment of protein localization to plasma membrane
GO:0043393	IEA:Ensembl	P	regulation of protein binding

KEGG Pathway Links

KEGG Pathway ID	Description
ko04144	Endocytosis
mmu04144	Endocytosis

REACTOME Pathway Links

REACTOME Pathway ID	Description
5893389	Chylomicron-mediated lipid transport
5893345	LDL-mediated lipid transport