LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP005380

Gene Information

Entrez Gene ID26119
Gene Namelow density lipoprotein receptor adaptor protein 1
Gene SymbolLDLRAP1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030424 ISS:BHF-UCLCaxon
GO:0009925 IDA:UniProtKBCbasal plasma membrane
GO:0009898 IDA:BHF-UCLCcytoplasmic side of plasma membrane
GO:0005829 IDA:UniProtKBCcytosol
GO:0005769 IDA:UniProtKBCearly endosome
GO:0005883 ISS:BHF-UCLCneurofilament
GO:0055037 IDA:BHF-UCLCrecycling endosome
GO:0035612 IDA:BHF-UCLFAP-2 adaptor complex binding
GO:0001540 IPI:BHF-UCLFbeta-amyloid binding
GO:0035615 IDA:BHF-UCLFclathrin adaptor activity
GO:0030276 IDA:UniProtKBFclathrin binding
GO:0050750 IPI:BHF-UCLFlow-density lipoprotein particle receptor binding
GO:0005546 IDA:BHF-UCLFphosphatidylinositol-4,5-bisphosphate binding
GO:0001784 IDA:UniProtKBFphosphotyrosine binding
GO:0030159 IMP:UniProtKBFreceptor signaling complex scaffold activity
GO:0035591 IDA:BHF-UCLFsignaling adaptor activity
GO:0042982 IMP:BHF-UCLPamyloid precursor protein metabolic process
GO:0042632 IMP:BHF-UCLPcholesterol homeostasis
GO:0008203 NAS:UniProtKBPcholesterol metabolic process
GO:0090205 IC:BHF-UCLPpositive regulation of cholesterol metabolic process
GO:0048260 IMP:UniProtKBPpositive regulation of receptor-mediated endocytosis
GO:0009967 IDA:GOCPpositive regulation of signal transduction
GO:0031623 IMP:BHF-UCLPreceptor internalization
GO:0006898 IDA:BHF-UCLPreceptor-mediated endocytosis
GO:0090118 IMP:BHF-UCLPreceptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
GO:0090003 IMP:BHF-UCLPregulation of establishment of protein localization to plasma membrane
GO:0043393 IMP:UniProtKBPregulation of protein binding
GO:0006810 NAS:UniProtKBPtransport
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04144Endocytosis
ko04144Endocytosis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6841Chylomicron-mediated lipid transport
REACT_6934LDL-mediated lipid transport
REACT_602Lipid digestion, mobilization, and transport
REACT_6823Lipoprotein metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins