LMPD Database

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LMP005338

UniProt Annotations

Entry Information
Gene Nameacyl-CoA synthetase medium-chain family member 3
Protein EntryACSM3_HUMAN
UniProt IDQ53FZ2
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q53FZ2-1; Sequence=Displayed; Name=2; IsoId=Q53FZ2-2; Sequence=VSP_028395, VSP_028396;
Catalytic ActivityATP + a carboxylate + CoA = AMP + diphosphate + an acyl-CoA.
CautionIt is uncertain whether Met-1 or Met-9 is the initiator.
CofactorName=Mg(2+); Xref=ChEBI
FunctionHas medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity).
Sequence CautionSequence=AAC31667.1; Type=Erroneous initiation; Evidence= ; Sequence=BAA03853.1; Type=Erroneous initiation; Evidence= ; Sequence=CAA56369.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the ATP-dependent AMP-binding enzyme family.
Subcellular LocationMitochondrion matrix .