LMPD Database

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LMP005214

UniProt Annotations

Entry Information
Gene Nameprostaglandin F2 receptor negative regulator
Protein EntryFPRP_MOUSE
UniProt IDQ9WV91
SpeciesMouse
Comments
Comment typeDescription
FunctionInhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). {ECO:0000250}.
SimilarityContains 6 Ig-like C2-type (immunoglobulin-like) domains. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
SubunitInteracts with CD9 and CD81. Also seems to interact with CD63, CD82 and CD151 (By similarity). {ECO:0000250}.