LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP005023

Gene Information

Entrez Gene ID51196
Gene Namephospholipase C, epsilon 1
Gene SymbolPLCE1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 IDA:UniProtKBCcytosol
GO:0005794 IEA:UniProtKB-KWCGolgi apparatus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0005509 IEA:InterProFcalcium ion binding
GO:0019899 IPI:UniProtKBFenzyme binding
GO:0005085 TAS:UniProtKBFguanyl-nucleotide exchange factor activity
GO:0004435 IDA:UniProtKBFphosphatidylinositol phospholipase C activity
GO:0004629 IDA:UniProtKBFphospholipase C activity
GO:0017016 TAS:UniProtKBFRas GTPase binding
GO:0005057 TAS:UniProtKBFreceptor signaling protein activity
GO:0000187 IDA:UniProtKBPactivation of MAPK activity
GO:0019722 NAS:UniProtKBPcalcium-mediated signaling
GO:0008283 NAS:UniProtKBPcell proliferation
GO:0007010 NAS:UniProtKBPcytoskeleton organization
GO:0006651 TAS:UniProtKBPdiacylglycerol biosynthetic process
GO:0007173 NAS:UniProtKBPepidermal growth factor receptor signaling pathway
GO:0032835 IMP:HGNCPglomerulus development
GO:0007507 TAS:UniProtKBPheart development
GO:0048016 TAS:UniProtKBPinositol phosphate-mediated signaling
GO:0043647 TAS:ReactomePinositol phosphate metabolic process
GO:0016042 IEA:UniProtKB-KWPlipid catabolic process
GO:0007200 IDA:UniProtKBPphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0006644 IC:UniProtKBPphospholipid metabolic process
GO:0007204 TAS:UniProtKBPpositive regulation of cytosolic calcium ion concentration
GO:0043547 TAS:GOCPpositive regulation of GTPase activity
GO:0007205 NAS:UniProtKBPprotein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007265 TAS:UniProtKBPRas protein signal transduction
GO:0001558 TAS:UniProtKBPregulation of cell growth
GO:0008277 IDA:UniProtKBPregulation of G-protein coupled receptor protein signaling pathway
GO:0045859 IDA:UniProtKBPregulation of protein kinase activity
GO:0046578 IDA:UniProtKBPregulation of Ras protein signal transduction
GO:0006940 TAS:UniProtKBPregulation of smooth muscle contraction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04024cAMP signaling pathway
hsa04015Rap1 signaling pathway
hsa04014Ras signaling pathway
hsa04919Thyroid hormone signaling pathway