LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP004831

UniProt Annotations

Entry Information
Gene Namepolymeric immunoglobulin receptor
Protein EntryPIGR_MOUSE
UniProt IDO70570
SpeciesMouse
Comments
Comment typeDescription
FunctionThis receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment (By similarity). {ECO:0000250}.
SimilarityContains 5 Ig-like V-type (immunoglobulin-like) domains. {ECO:0000305}.
Subcellular LocationCell membrane; Single-pass type I membrane protein.
Subcellular LocationSecretory component: Secreted.